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Ephedrine Powder

Ephedrine Powder

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Description

Ephedrine is a naturally occuring central nervous system stimulant obtained

from the plant _Ephedra equisetina_. It is now also produced by chemical

synthesis, the synthetic product being marketed in the form of its salt,

ephedrine sulfate; it occurs as a white crystalline powder with a bitter

taste, soluble in water and very soluble in alcohol. Ephedrine is closely

related in structure to methamphetamine, although its CNS actions are much

less potent and also longer-acting than those of the amphetamines. Its

peripheral stimulant actions are similar to but less powerful than those of

epinephrine (also called adrenaline), a hormone produced in the body by the

adrenal glands.

 

Ephedrine has moderately potent bronchial muscle relaxant properties, and

therefore is used for symptomatic relief in milder cases of asthmatic

attack; it is also used to reduce the risk of acute attacks in the treatment

of chronic asthma. The typical adult dose range is 30-60 mg taken orally,

three to four times per day, in the form of tablets. Ephedrine in the form

of nose drops is also widely used to relieve nasal congestion associated

with upper respitory tract illnesses. It is also used to treat low blood

pressure, because it constricts blood vessels and stimulates certain actions

of the heart. Common side effects are qualitatively similar to those

produced by amphetamines and are generally milder. Higher doses (overdose)

can cause restlessness and anxiety, dizziness, insomnia, tremor, rapid

pulse, sweating, respiratory difficulties, confusion, hallucinations,

delerium, and (very infrequently) convulsions. The most dangerous symptoms

of overdose are abnormally high blood pressure and rapid, irregular

heartbeat. A dose of ephedrine only two to three times the theraputic

maximum can cause a significant increase in blood pressure. The elderly are

particularly sensitive to overdose, and there have been a few deaths among

such patients. Finally, a number of instances of psychosis, clinically

similar to amphetamine psychosis, have resulted from chronic high-dose

abuse; other effects of chronic abuse have not been adequately studied.

 

Tolerance develops to the main effects of ephedrine; however, temporary

abstinence restores sensitivity.

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